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1.What is the Carbenicillin disodium ?
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Carbenicillin is a broad-spectrum carboxypenicillin antibiotic. It is active against Gram-negative and certain Gram-positive bacteria, including S. pyogenes, S. epidermidis, P. mirabilis, P. vulgaris, E. coli, and P. aeruginosa (MICs = 0.19, 1.56, 1.56, 3.12, 3.12, and 50 μg/ml, respectively). It is also active against penicillinase-producing and non-producing strains of S. aureus (MICs = 1.56 and 12.5 μg/ml, respectively). Carbenicillin is protective against systemic S. pyogenes, P. vulgaris, E. coli, and S. aureus infection in a mouse model of systemic lethal infection with 50% protective dose (PD50) values of 7.8, 224, 19.3, and 34 mg/kg, respectively. It also decreases viable colony counts in the kidney in a rat model of P. vulgaris or E. coli urinary tract infection when administered at a dose of 100 mg/kg. Formulations containing carbenicillin have previously been used in the treatment of upper and lower urinary tract infections and prostatitis.
2.What is the CAS number for Carbenicillin disodium ?
The CAS number of Carbenicillin disodium is 4800-94-6.
3.What are another words for Carbenicillin disodium ?
Synonyms?for?Carbenicillin disodium 4800-94-6:4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt,(2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2a,5a,6b)]-;Malonamic acid,N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-2-phenyl-,disodium salt (7CI,8CI);Anabactyl;BRL 2064;CP 15639-2;Carbapen;Carbecin;Carbenicillin disodium salt;Carbenicillin sodium;Carbenicilline disodium;Carboxybenzylpenicillin sodium;Disodium (a-carboxybenzyl)penicillin;Disodium carbenicillin;Fugacillin;Geopen;Hyoper;Microcillin;Piopen;Pyopen;Sodium carbenicillin;a-Carboxybenzylpenicillin disodiumsalt;a-Carboxybenzylpenicillin sodiumsalt;
4.What is Carbenicillin disodium (4800-94-6) used for?
Carbenicillin disodium salt is a water-soluble antibiotic which is effective against gram-negative bacteria.Carbenicillin disodium salt is widely utilized as an antibiotic which is used to control bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. It has been involved in the study of the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.
InChI:InChI=1/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2
Relevant articles related to Carbenicillin disodium:
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Intermediates for preparing α-carboxy-α-(3-thienyl)penicillin and cephalosporin derivatives |
- , (2008/06/13) |
5.Buy Carbenicillin disodium with the best price .
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